WHO has published a new position paper about typhoid vaccines. The update uses new information about typhoid cases, disease impact and vaccine results. It focuses mainly on typhoid conjugate vaccines, often called TCVs.
Several countries now have experience using these vaccines after introducing them. Evidence shows how one dose protects people over time and how age can affect protection. Protection can also vary between places with different disease patterns. The paper also reviews information about booster doses. It notes the spread of antibiotic-resistant Salmonella Typhi. The document brings this evidence together for health officials. The full paper has 15 pages and replaces WHO’s advice from 2018.